Mihaela Gherghiceanu MD PhD – Research group leader (CSI)
- Associate Professor for Cellular Molecular Biology and Histology at Carol Davila University of Medicine and Pharmacy
- Vicepresident of the Romanian Electron Microscopy Society
Daciana Marta, MSc, PhD – Associate researcher (CSII)
Laura Ceafalan MD, PhD – Associate researcher (CSII)
- Specialist of Laboratory Medicine
- Assistant Professor of Cellular Molecular Biology and Histology at Carol Davila University of Medicine and Pharmacy
Emanuel Fertig, MD, PhD – Associate researcher (CSIII)
- Resident in Clinical Haematology
Alexandru Popescu, MD – Assistant researcher
- Teaching assistant of Cellular Molecular Biology and Histology at Carol Davila University of Medicine and Pharmacy
ANCS PN 16.22.02.02/2016.02.02
|Involvment of telocytes in the process of regeneration
Project director: Mihaela Gherghiceanu
|2016-2017||ANCS PN 16.22.03.02
|The molecular architecture of the glomerular basement membrane in glomerular immune diseases
Project director: Marta Daciana
|2016-2017|| ANCS PN 16.22.01.03
|Traffic of miRNA by ectosomes in hematological malignancies
Project director: Tudor Emanuel Fertig
|2016-2018||Bilateral cooperation Romania – Belgium
|Traffic and signalling of calreticulin in myeloproliferative neoplasms
Project director: Tudor Emanuel Fertig (IVB)
Partner: Stefan N. Constantinescu (Université catholique de Louvain)
Equipped with an Olympus MegaView III CCD, is our main diagnostic tool, allowing fast and qualitative evaluation of plastic embedded specimens.
Is employed for more demanding applications, such as tomography of chemically fixed specimens. Image acquisition is done by an Olympus MegaView G2 CCD and recently it was fitted with a Tecnai iCorr module for correlative light and electron microscopy (CLEM), which allows merging of fluorescence and transmission electron microscopy images.
(The first of its kind in Romania) Enables us to visualize cellular structures and isolated macromolecular assemblies in remarkable detail, in 2 and 3-dimensions. This TEM is equipped to handle metal coated and chemically fixed specimens, but also cryogenically frozen samples, a technique which preserves the native, hydrated structure. This system was acquired through POSCCE 2.2.1 Grant 633/2014 (ARMED).
(This too, the first of its kind in Romania) Is the latest iteration of a Nobel Prize winning technology, one that literally sheds new light on the dynamics of fluorescently-tagged molecules in living cells. It uses Stimulated Emission Depletion (STED), in which a laser selectively activates and deactivates fluorophores, to obtain nanoscale resolutions, thereby overcoming the limits of optical microscopy. This system was acquired through POSCCE 2.2.1 Grant 633/2014 (ARMED).
(Leica EM GP and FEI Vitrobot Mark IV cryoplungers, Leica EM PACT2 high pressure freezer, Leica EM UC7 cryo ultramicrotome, Leica EM AFS2 cryo-substitution system etc). This equipment was acquired through POSCCE 2.2.1 Grant 633/2014 (ARMED).
- Tissue culture facility offers the necessary logistics for cell culture, transfections and in the future, the use of viral vector systems.
- Thermo Scientific Sorvall WX+ ultracentrifuge acquired through POSCCE 2.2.1 Grant 633/2014 (ARMED).