{"id":12389,"date":"2025-07-15T08:25:05","date_gmt":"2025-07-15T08:25:05","guid":{"rendered":"https:\/\/www.ivb.ro\/?page_id=12389"},"modified":"2026-01-15T14:29:58","modified_gmt":"2026-01-15T14:29:58","slug":"program-nucleu-2023-2026","status":"publish","type":"page","link":"https:\/\/www.ivb.ro\/en\/program-nucleu-2023-2026","title":{"rendered":"Programul Nucleu"},"content":{"rendered":"
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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tThe Program's Nucleus 2023-2026\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h4>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tMolecular mechanisms in non-communicable diseases in major cancer in the pathology of degenerative disease of the size of the gene in the immune \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Acronym: MEMOGEN<\/strong><\/span><\/p>

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Program Director: Prof. Dr Mihail Eugen Hinescu <\/strong><\/span><\/p>

The objectives of the program:<\/strong><\/span><\/p>

Ob1. The identification of the mechanisms and molecular determinants in the pathogenesis of non-communicable diseases, the impact of diagnosis and treatment<\/span><\/p>

Ob2. The identification and\/or validation of targets for molecular cancer in order to adapt the therapeutic strategy<\/span><\/p>

Ob3. The maintenance and improvement of the human resources senior specialist in PATHOLOGY, "Victor Babe\u015f"<\/span><\/p>

Ob4. The maintenance and development of the infrastructure of the CD of INCD \"Victor Babe\u015f\"<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t

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OBJECTIVE 1<\/span><\/span><\/h4><\/div><\/div><\/div><\/div>

Project 1: advanced Strategy for the exploration of the signatures of the molecular impact of diagnosis and therapy in epileptic encephalopathies of children<\/span>
Project 2: the Sarcopenia-associated neurodegenerative diseases: the definition of the molecular basis of cross-linking on the axis of the brain-to-striated muscle in order to identify prognostic factors and therapeutic targets<\/span>
Project 3: the Role of the caveolinei-1 amyloidosis, vascular associated with the aging process<\/span>
Proiect 4: Triada func\u021bional\u0103 \u00een psoriazisul experimental murin: sistem imun \u2013 piele<\/span><\/p>

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OBJECTIVE 2<\/span><\/span><\/h4><\/div><\/div><\/div><\/div>

Project 5: The area to be mediated by the lncRNA \u2013 targeted therapy in pancreatic cancer<\/span><\/p>

Project 6: A therapeutic combination based on the transfer adopted by the cells and NK-cells, and an inhibitor of TGFBRI\/II melanoma, metastatic<\/span><\/p>

Project 7: Approaches to the molecular 3D model (sferoizi s) edited a gene by the method of CRISPR\/Cas9 in the development of solutions for personalized medicine in cancer<\/span><\/p>

Project 8: Genes of the stress response targets for therapeutic radiotherapy and photodynamic therapy of carcinoma of the colon<\/span><\/p><\/div><\/div><\/div><\/div><\/div><\/section>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Project components financed<\/span><\/h4><\/div><\/div>

ID<\/strong><\/span><\/p><\/td>

Title<\/span> <\/strong><\/p><\/td>

Project lead<\/span> <\/strong><\/p><\/td><\/tr>

Objective 1. The identification of the mechanisms and molecular determinants in the pathogenesis of non-communicable diseases, the impact of diagnosis and treatment<\/strong><\/span><\/p><\/td><\/tr>

PN 23.16.01.01<\/span><\/p><\/td>

The role of the caveolinei-1 amyloidosis, vascular associated with the aging process<\/a><\/p><\/td>

CSI Dr. Mihaela Gherghiceanu,<\/span><\/p><\/td><\/tr>

PN 23.16.01.02<\/span><\/p><\/td>

Sarcopenia-associated neurodegenerative diseases: the definition of the molecular basis of the inter-relationships onto the axis of the brain-to-striated muscle in order to identify prognostic factors and therapeutic targets<\/a><\/p><\/td>

Laura Cristina-Ceafalan<\/span><\/p><\/td><\/tr>

PN 23.16.01.03<\/span><\/p><\/td>

Triada func\u021bional\u0103 \u00een psoriazisul experimental murin: sistem imun \u2013 piele \u2013 intestin<\/a><\/p><\/td>

Carolina Constantin<\/span><\/p><\/td><\/tr>

Objective 2. The identification and\/or validation of targets for molecular cancer in order to adapt the therapeutic strategy<\/strong><\/span><\/p><\/td><\/tr>

PN 23.16.02.01<\/span><\/p><\/td>

The genes of the stress response targets for therapeutic radiotherapy and photodynamic therapy of carcinoma of the colon<\/a><\/p><\/td>

Gina Manda<\/span><\/p><\/td><\/tr>

PN 23.16.02.02<\/span><\/p><\/td>

Approach to the therapeutic combination based on the transfer of the care of the cells and NK-cells, and an inhibitor of TGFBRI\/II melanoma, metastatic<\/a><\/p><\/td>

Dr Gheorghita Isvoranu<\/span><\/p><\/td><\/tr>

PN 23.16.02.03<\/span><\/p><\/td>

Approaches to the molecular 3D model (sferoids) edited a gene by the method of CRISPR\/Cas9 in the development of solutions for personalized medicine in cancer<\/a><\/p><\/td>

Codrici Elena<\/span><\/p><\/td><\/tr><\/tbody><\/table><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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