{"id":521,"date":"2020-08-10T07:44:46","date_gmt":"2020-08-10T07:44:46","guid":{"rendered":"http:\/\/ivb.ro\/?page_id=521"},"modified":"2025-01-28T11:37:39","modified_gmt":"2025-01-28T11:37:39","slug":"publicatii-biobaza","status":"publish","type":"page","link":"https:\/\/www.ivb.ro\/en\/publicatii-biobaza","title":{"rendered":"Publications"},"content":{"rendered":"
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Book chapters & Publications<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Therapeutic potential of interleukin-21 in cancer. Gheorghita Isvoranu, Marioara Chiritoiu-Butnaru, Front. Immunol. 2024, 15, doi.org\/10.3389\/fimmu.2024.1369743<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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Immune portrayal of a new therapy targeting microbiota in an animal model of psoriasis. Surcel Mihaela, Constantin Carolina, Munteanu Adriana Narcisa, Costea Diana Antonia, Isvoranu Gheorghita, Codrici Elena, Popescu Ionela Daniela, Tanase Cristiana, Ibram Alef, Neagu Monica. Journal of Personalized Medicine<\/em> 2023, 13 (11): 1556; DOI:\u00a010.3390\/jpm13111556<\/a><\/p>

In Vivo Acute Toxicity and Immunomodulation Assessment of a Novel Nutraceutical in Mice<\/a>. Tatiana Onisei, Bianca-Maria Tih\u0103uan, Georgiana Dolete, M\u0103d\u0103lina Axinie, Manuela R\u0103scol, Gheorghi\u021ba Isvoranu. Pharmaceutics<\/em> 2023, 15(4): 1292; DOI:\u00a010.3390\/pharmaceutics15041292<\/a><\/p>

Behaviour testing in two different knockout mouse strains related to chronic inflammation and oxidative stress<\/a>. Dobri Ana-Maria, Isvoranu Gheorghi\u021ba, Enciu Ana-Maria, Hinescu Mihail E. Cellular and Molecular Biology<\/em> 2023, 69(3): 113-117; DOI:\u00a010.14715\/cmb\/2023.69.3.15<\/a><\/p>

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Healthy ageing reflected in innate and adaptive immune parameters. Munteanu NA, Surcel M, Isvoranu G, Constantin C, Neagu M. Clinical Interventions in Aging<\/em> 2022; 17:1513-1526, https:\/\/doi.org\/10.2147\/CIA.S375926<\/a><\/h2>

Cardioprotective Mechanisms of Interrupted Anesthetic Preconditioning with Sevoflurane in the Setting of Ischemia\/Reperfusion Injury in Rats. Popescu MR, Pavel B, Isvoranu G, Ceafalan LC, Panaitescu AM, Sava RI, Vlad A, Zagrean L. Appl. Sci.<\/em>\u00a02022,\u00a012<\/em>(3), 1476; https:\/\/doi.org\/10.3390\/app12031476<\/strong><\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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Gait Analysis Using Animal Models of Peripheral Nerve and Spinal Cord Injuries. Gheorghita Isvoranu, Emilia Manole, Monica Neagu. Biomedicines<\/em>, 2021, 9(8): 1050. DOI:\u00a010.3390\/biomedicines9081050<\/a><\/p>

Therapeutic potential of interleukin-15 in cancer (Review), Gheorghi\u021ba Isvoranu, Mihaela Surcel, Adriana Narcisa Munteanu, Ovidiu Gabriel Bratu, Florentina Ionita\u2011Radu, Monica Teodora Neagu, Marioara Chiritoiu\u2011Butnaru, Exp Ther Med.<\/em>\u00a02021, 22(1):675; DOI:\u00a010.3892\/etm.2021.10107<\/a><\/p>

Unconventional Therapy with IgY in a Psoriatic Mouse Model Targeting Gut Microbiome. Mihaela Surcel<\/a>,\u00a0Adriana Munteanu<\/a>,\u00a0Gheorghita Isvoranu<\/a>\u00a0,\u00a0Alef Ibram<\/a>, Constantin Caruntu<\/a>,\u00a0Carolina Constantin<\/a>\u00a0,\u00a0Monica Neagu<\/a>. J. Pers. Med.\u00a02021, 26;11(9):841, DOI:\u00a010.3390\/jpm11090841<\/a><\/p>

NK cells in psoriasiform dermatitis. From psoriatic site to peripheral blood, through secondary immune organs. Mihaela Surcel, Adriana Narcisa Munteanu, Gheorghi\u021ba Isvoranu<\/u>, Carolina Constantin, Teodora Supeanu, Ovidiu Bratu, Mihail Alecu, Monica Neagu. Dermato Venerol, 66(1):7-16, 2021<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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\u2022 The effects of two different anesthesia and analgesia techniques on NK cell cytotoxicity in patients undergoing surgery for colorectal cancer. Izadora Zaharescu, Gheorghi\u021ba Isvoranu, Rusu Elena, Cosmin Moldovan, Cristiana Tanase, Rom Biotechnol Lett. 2020; 25(2):1482-1487, doi: 10.25083\/rbl\/25.2\/1482.1487<\/span>
\u2022 Natural Killer Cells in Type 1 Diabetes \u2013 Phenotypic Characteristics. Isvoranu Gheorghi\u0163a, Manole Emilia, Surcel Mihaela, Munteanu Adriana Narcisa, Neagu Monica Teodor, Filodiritto Editore \u2013 Proceedings 6th InterDIAB 2020 – International Conference on Interdisciplinary Management of Diabetes Mellitus and its Complications, pp. 189-194, 2020<\/span>

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  • Toxic effects of non-acute lead exposure on animal model, Gheorghita Isvoranu, Daniela Ionela Popescu, Elena Codrici, Simona Mihai, Ana-Maria Enciu, Gina Manda, Marco Peretto, Cristiana Tanase, SIMI 2019 Proceeding book, DOI: http:\/\/doi.org\/10.21698\/simi.2019.fp35\u00a0<\/span><\/li><\/ul>

    \u2022 Reinforcing involvement of NK cells in psoriasiform dermatitis animal model. Mihaela Surcel, Adriana Munteanu, Radu-Ionu\u021b Huic\u0103, Gheorghi\u021ba Isvoranu, Ioana P\u00eervu, Carolina Constantin, Ovidiu Bratu, Constantin C\u0103runtu, Isadora Zaharescu, Lucica Sima, Marieta Costache, Monica Neagu. August 30, 2019, https:\/\/doi.org\/10.3892\/etm.2019.79671.<\/span>
    \u2022 Peripheral immune cell markers in children with recurrent respiratory infections in the absence of primary immunodeficiency, Adriana Narcisa Munteanu, Mihaela Surcel, Radu-Ionu\u021b Huic\u0103, Gheorghi\u021ba Isvoranu, Carolina Constantin, Ioana Ruxandra P\u00eervu, Carmen Chifiriuc, Coriolan Ulmeanu, Cornel Ursaciuc, Monica Neagu, Exp. Ther. Med., 18;3:1693-1700, 2019, https:\/\/doi.org\/10.3892\/etm.2019.7714<\/span>
    \u2022 NK monitoring in cutaneous melanoma – new dynamic biomarker. Gheorghi\u021ba Isvoranu, Mihaela Surcel, Radu-Ionu\u021b Huic\u0103, Adriana Narcisa Munteanu, Ioana Ruxandra P\u00eervu, Dan Ciotaru, Carolina Constantin, Ovidiu Bratu, Monica Neagu, Cornel Ursaciuc. Oncology Letters, 17;5:4197-4206, 2019, https:\/\/doi.org\/10.3892\/ol.2019.10069<\/span>


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    \u2022 Phenotypic changes of lymphocyte populations in psoriasiform dermatitis animal model. Mihaela Surcel, Radu-Ionu\u021b Huic\u0103, Adriana Narcisa Munteanu, Gheorghi\u021ba Isvoranu, Ioana Ruxandra P\u00eervu, Dan Ciotaru, Carolina Constantin, Ovidiu Bratu, Constantin C\u0103runtu, Monica Neagu, Cornel Ursaciuc. Exp. Ther. Med., 17;2:1030-1038, 2018, https:\/\/doi.org\/10.3892\/etm.2018.6978<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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    \u2022 Immune status in skin carcinoma bearing mice. Bogdan Marinescu, Alin Birtoiu, Mihaela Surcel, Florina Cionca, Gheorghita Isvoranu. Rom. Arch. Microbiol. Immunol., 76 (1), 36-40, 2017<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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    \u2022 Cytostatic therapy on tumor bearing mice: biochemical and hematological aspects. Laurentiu Anghelache, Bogdan Marinescu, Gheorghita Isvoranu, Dan Cr\u00eenganu, Andrei Niculae, Ovidiu Bratu, Modern medicine, 23, 1:26-32, 2016<\/span>
    \u2022 Exposure of Human Endothelial Progenitors to Sevoflurane Improves Their Survival Abilities. Munteanu A, Gilca M, Isvoranu G, Surcel M, Ceafalan L, Manda G. Rev Romana Med Lab. 2016;24(2):177-86. DOI:10.1515\/rrlm-2016-0022<\/span>

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    \u2022 Immunotherapy in cancer – in vivo study of the antitumor activity of the IL-15\/IL-15R alfa combination in an experimental model of melanoma. Gheorghi\u0163a Isvoranu, B. Marinescu, Mihaela Surcel, C. Ursaciuc, Gina Manda, Farmacia, 63;5:631-636, 2015<\/span>
    \u2022 In vivo study of MAL-PDT using fluorescence spectra. Emil Petrescu, Mihaela Antonina Calin, Bogdan Marinescu, Cristina Cirtoaje, , U.P.B. Sci. Bull., Series A, 7(2):269-276, 2015<\/span>
    \u2022 Toxicity of L-DOPA coated iron oxide nanoparticles in intraperitoneal delivery setting – preliminary preclinical study. Maria Victoria Comanescu, Mihaela Andreea Mocanu, Laurentiu Anghelache, Bogdan Marinescu, Florian Dumitrache, Anca-Daniela Badoi, Gina Manda, Rom. J. Morphol. Embryol, 56(2 Suppl):3-6, 2015<\/span>
    \u2022 New echocardiographic protocol for the assesment of experimental myocardial infarction in rats. Ruxandra Dragoi Galrinho, Andrea Olivia Ciobanu, Roxana Cristina Rimbas, Catalin Manole, Bogdan Marinescu, Dragos Vinereanu, Maedica a Journal of Clinical Medicine, 10(2):85-90, 2015<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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    \u2022 The redox biology network in cancer pathophysiology and therapeutics. Manda G, Isvoranu G, Comanescu MV, Manea A, Debelec Butuner B, Korkmaz KS, Redox Biol., 25;5:347-357, 2015<\/span>
    \u2022 Geam\u0103nu Panc\u0103 A, Popa-Cherecheanu A, Marinescu B, Geam\u0103nu CD, Voinea LM. Retinal toxicity associated with chronic exposure to hydroxychloroquine and its ocular screening. Review. J Med Life.<\/span>
    7(3):322-326, 2014<\/span>
    \u2022 Multiple Benefic Effects of the Systemic Exposure to the Hydroxychloroquine Sulfate Aida (Panc\u00e3)<\/span>
    Geam\u00e3nu1, Alina Popa-Cherecheanu1, B. Marinescu, D.C. Geam\u00e3nu ,Liliana Voinea. Modern<\/span>
    Medicine. 21(3):180-185, 2014<\/span>
    \u2022 Spectral analysis of methyl-aminolevulinate based photodynamic therapy using fractionared light.<\/span>
    Cristina Cirtoaje, Emil Petrescu, Mihaela Antonia Calin, Gina Izvoranu; U.P.B.Sci.Bull., Seria A, 76(4),<\/span>
    191-198, 2014<\/span>
    \u2022 Hematology references for three laboratory mice strain. Bogdan Marinescu, Gheorghita Isvoranu,<\/span>
    Laurentiu Anghelache, Florina Cionca; Roum Arch Microbiol Immunol, 73(1-2); 30-4, 2014<\/span>

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    \u2022 Consequences of the tandem IL-21 and IL-15 on mouse NK cells in vitro. Gheorghi\u0163a Isvoranu, Mihaela<\/span>
    Surcel, B. Marinescu, Gina Manda, L. Albulescu, Maria Dobre, C.Ursaciuc, C. Tesio., Rev. Rom. Med.<\/span>
    Vet., vol 22, nr. 1\/2012<\/span>

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    \u2022 The efficiency of antitumoural activity of combination IL-15\/IL-15R alfa in experimental model of<\/span>
    carcinoma in vivo, Gheorghi\u0163a Isvoranu, B. Marinescu, Mihaela Surcel, Gina Manda, Maria Dobre,<\/span>
    C.Ursaciuc, C. Tesio. Rev. Rom. Med. Vet., vol 21, nr. 4\/2011<\/span>
    \u2022 Dynamics of endothelial progenitor cells following sevoflurane preconditioning. Mihaela Popescu,<\/span>
    Adelina Munteanu, Gheorghi\u0163a Isvoranu, Laura Suciu, Bogdan Pavel, Bogdan Marinescu, Leon<\/span>
    Z\u0103grean. Romanian Archives of Microbiology and Immunology. No. 3, 2011<\/span>

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    \u2022 Experimental model of chemically induced skin carcinogenesis in mice, B. Marinescu, Gheorghi\u0163a <\/span>Isvoranu, Carolina Constantin, C. Coman, Sabina Zurac, C. C\u0103runtu, D. Boda, Monica Neagu, Mihaela <\/span>C\u0103lin. Rev. Rom. Med. Vet. vol. 20, nr. 4, 97-104, 2010<\/span>
    \u2022 The ethics of animal testing. B. Marinescu, C. Coman. Romanian Journal of Bioethics, 8(3):96-103,<\/span>2010.<\/span>

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    \u2022 Lymphocyte Updates \u2013 Cancer, Autoimmuniy and Infection. Edited by Gheorghita Isvoranu, ISBN 978-<\/span>953-51-3344-5, Print ISBN 978-953-51-3343-8, 190 pages, InTech, 2017 DOI: 10.5772\/66613<\/span>
    \u2022 Evaluarea etica si autorizarea proiectelor ce utilizeaza animale in proceduri experimentale. Coman <\/span>Cristin, Gonciarov Magda, Bogdan Marinescu, ISBN 978-606-23-0745-5, Editura PRINTECH, <\/span>Bucuresti, 2017<\/span>
    Capitole de carte:<\/span>
    \u2022 Chapter Schwann Cell Plasticity in Peripheral Nerve Regeneration after Injury. Emilia Manole, Alexandra<\/span>
    Eugenia Bastian, Ana Maria Oproiu, Monica Teodora Neagu, Carolina Constantin and Gheorghita<\/span>
    Isvoranu, IntechOpen, 2020, DOI: 10.5772\/intechopen.91805<\/span>
    \u2022 The memory activation of NK cells – new methods in cancer immunotherapy. Gheorghi\u0163a Isvoranu.<\/span>
    Capitolul 10 in cartea Immunotherapy – Myths, Reality, Ideas, Future. Edited by Krassimir Metodiev<\/span>
    ISBN 978-953-51-3106-9, Print ISBN 978-953-51-3105-2, InTech, 2017 DOI:10.5772\/66555<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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    Cereri brevete :<\/span><\/span><\/p>

    • Metod\u0103 de stabilire a unui set de interleukine-citokine-chemokine imunologic relevante \u00een model animal de psoriazis tratat cu IgY ob\u021binut din oul hiperimun. Inventatori – Cristiana T\u0103nase,\u00a0Monica Neagu, Elena Codrici, Daniela Popescu, Ana-Maria Enciu, Gheorghi\u021ba Isvoranu<\/u>,\u00a0Mihaela Surcel, Adriana Munteanu, Viorica Chirciu, Alef Ibram; Cerere brevet de inventie OSIM A000678\/11.11.2021<\/span>

      \u00a0<\/p><\/li>

    • Linie celular\u0103 reporter pentru testarea activit\u0103\u021bii unor modulatori ai sintezei \u0219i secre\u021biei proteinei IL-1\u03b2. Marioara Chiritoiu-Butnaru, Gabriela Chiritoiu, Simona Ghenea, Gheorghita Isvoranu<\/u>. Cerere brevet de inventie OSIM Nr. A\/00687\/27.10.2022<\/span><\/p><\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

      Book chapters & Publications Articles 2024 Therapeutic potential of interleukin-21 in cancer. Gheorghita Isvoranu, Marioara Chiritoiu-Butnaru, Front. Immunol. 2024, 15, doi.org\/10.3389\/fimmu.2024.1369743 ARTICLES 2023 Immune portrayal of a new therapy targeting microbiota in an animal model of psoriasis. Surcel Mihaela, Constantin Carolina, Munteanu Adriana Narcisa, Costea Diana Antonia, Isvoranu Gheorghita, Codrici Elena, Popescu Ionela Daniela, Tanase… <\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-521","page","type-page","status-publish","hentry"],"yoast_head":"\nPublicatii Biobaza - National Institute of Pathology Victor Babe\u015f - Bucharest<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ivb.ro\/en\/publicatii-biobaza\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publicatii Biobaza - National Institute of Pathology Victor Babe\u015f - Bucharest\" \/>\n<meta property=\"og:description\" content=\"Book chapters & Publications Articles 2024 Therapeutic potential of interleukin-21 in cancer. 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