{"id":594,"date":"2020-08-10T09:17:46","date_gmt":"2020-08-10T09:17:46","guid":{"rendered":"http:\/\/ivb.ro\/?page_id=594"},"modified":"2024-05-14T13:24:46","modified_gmt":"2024-05-14T13:24:46","slug":"cost-action-ca-17103-cell-biology","status":"publish","type":"page","link":"https:\/\/www.ivb.ro\/en\/cost-action-ca-17103-cell-biology","title":{"rendered":"COST Action CA 17103 Cell Biology"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"594\" class=\"elementor elementor-594\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4f220512 elementor-section-content-middle elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4f220512\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-458bc38d\" data-id=\"458bc38d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-36d7874e elementor-view-framed elementor-shape-circle elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"36d7874e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-star\" viewbox=\"0 0 576 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M259.3 17.8L194 150.2 47.9 171.5c-26.2 3.8-36.7 36.1-17.7 54.6l105.7 103-25 145.5c-4.5 26.3 23.2 46 46.4 33.7L288 439.6l130.7 68.7c23.2 12.2 50.9-7.4 46.4-33.7l-25-145.5 105.7-103c19-18.5 8.5-50.8-17.7-54.6L382 150.2 316.7 17.8c-11.7-23.6-45.6-23.9-57.4 0z\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h4 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tCOST CA 17103\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h4>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tThe Delivery of the Antisense RNA Therapeutics\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-21342ce elementor-widget elementor-widget-text-editor\" data-id=\"21342ce\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\"><span style=\"color: #000000;\">Oligonucleotidele antisens (ASO) sunt o nou\u0103 clas\u0103 de medicamente care, printr-o \u021bintire foarte specific\u0103, ar putea corecta defectele genetice pentru boli mo\u0219tenite rare, pot modula boli autoimune sau neurodegenerative sau pot viza tumori\/virusuri. Cu toate acestea, doar c\u00e2teva dintre astfel de medicamente sunt \u00een prezent pe pia\u021b\u0103 \u0219i cele care sunt au o eficien\u021b\u0103 mai mica fata de cum se a\u0219tepta. Principalul obstacol privind eficacitatea lor pare s\u0103 fie livrarea lor deficitar\u0103 c\u0103tre \u021besuturile \u021bint\u0103, \u00cen timp ce cercetarea transla\u021bional\u0103 asupra ASO este \u00een cre\u0219tere, se cunosc foarte pu\u021bine despre mecanismele prin care ASO sunt preluate de diferite \u021besuturi \u0219i celule specifice.<\/span><\/p><p style=\"text-align: left;\"><span style=\"color: #000000;\">Scopul principal al Ac\u021biunii COST Delivery of Antisens ARN Therapeutics (DARTER) este de a utiliza o re\u021bea de cercetare interdisciplinar\u0103 care reune\u0219te cercet\u0103tori \u0219i inovatori pentru investigarea administr\u0103rii terapiei cu acizi nucleici cu scopul de a permite medicamentelor cu acid nucleic care vizeaz\u0103 ARN-ul s\u0103 \u00ee\u0219i ating\u0103 \u00eentregul poten\u021bial \u0219i s\u0103 devin\u0103 o op\u021biune terapeutic\u0103 principal\u0103.<\/span><\/p><p style=\"text-align: left;\"><span style=\"color: #000000;\">DARTER va ac\u021biona prin intermediul a 3 grupuri de lucru cu obiective de cercetare (strategii de livrare, sisteme model, siguran\u021b\u0103 \u0219i toxicologie) \u0219i un grup de consolidare a capacit\u0103\u021bilor (comunicare cu p\u0103r\u021bile interesate) cu obiectivul de a ob\u021bine un consens privind protocoalele de evaluare a furniz\u0103rii \u0219i a toxicologiei ASO \u00een acela\u0219i timp urmarind \u0219i formarea de noi cercet\u0103tori \u00een domeniu.\u00a0<\/span><\/p><p style=\"text-align: left;\"><span style=\"color: #000000;\">Re\u021beaua DARTER COST reune\u0219te participan\u021bi din \u021b\u0103rile COST \u0219i mai mul\u021bi parteneri interna\u021bionali, inclusiv academicieni, parteneri industriali, reprezentan\u021bi ai pacien\u021bilor \u0219i clinicieni \u0219i este deschis\u0103 altor p\u0103r\u021bi interesate.<\/span><\/p><p style=\"text-align: left;\">\u00a0<\/p><p style=\"text-align: left;\"><span style=\"color: #000000;\">https:\/\/www.cost.eu\/actions\/CA17103\/<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3f3601f elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3f3601f\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9f5b92d\" data-id=\"9f5b92d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f1c65aa elementor-widget elementor-widget-shortcode\" data-id=\"f1c65aa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\"><iframe src=\"https:\/\/www.cost.eu\/actions\/CA17103\/#tabs|Name:management-committee\" width=\"50px\" height=\"1800px\" frameborder=\"1\" scrolling=\"yes\" align=\"left\"> <\/iframe><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>COST CA 17103 Delivery of Antisense RNA Therapeutics Oligonucleotidele antisens (ASO) sunt o nou\u0103 clas\u0103 de medicamente care, printr-o \u021bintire foarte specific\u0103, ar putea corecta defectele genetice pentru boli mo\u0219tenite rare, pot modula boli autoimune sau neurodegenerative sau pot viza tumori\/virusuri. Cu toate acestea, doar c\u00e2teva dintre astfel de medicamente sunt \u00een prezent pe pia\u021b\u0103&hellip; <\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-594","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>COST Action CA 17103 Cell Biology - National Institute of Pathology Victor Babe\u015f - Bucharest<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ivb.ro\/en\/cost-action-ca-17103-cell-biology\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"COST Action CA 17103 Cell Biology - National Institute of Pathology Victor Babe\u015f - Bucharest\" \/>\n<meta property=\"og:description\" content=\"COST CA 17103 Delivery of Antisense RNA Therapeutics Oligonucleotidele antisens (ASO) sunt o nou\u0103 clas\u0103 de medicamente care, printr-o \u021bintire foarte specific\u0103, ar putea corecta defectele genetice pentru boli mo\u0219tenite rare, pot modula boli autoimune sau neurodegenerative sau pot viza tumori\/virusuri. 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