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Before Alzheimer’s Disease

Before Alzheimer’s Disease: novel mechanism of amyloid precursor protein signaling in adult healthy brain


Institution: Victor Babes National Institute of Research Development in the Pathology Domain and Biomedical Sciences
PI: Dr. Ana-Maria Enciu, MD, PhD
Funding: State Bugdet through  Romanian National Authority for Scientific Research and Innovation CNCS-UEFISCDI
Contract no: PN-II-RU-TE-2014-4-1534
Main objective: Demonstration of APP oligomerization in healthy adult mouse brain, conditionned by membrane microdomains. We propose here a new mechanism of APP signaling and bring the first arguments and the technical means for a more complex demonstration.


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