ABOUT US – CELL BIOLOGY

In the present work, our research is focused on understanding the details of the cellular and molecular mechanisms of physiological and pathological findings in 4 distinct themes of the research.

• Leukemia: a mechanism for the conversion of progenitor hematopoietici preleucemici in the cells of the originator of leukemia, and the establishment of new methods for the detection of mutations in order to keep track of minimal residual disease (MRD), and the himerismul after bone marrow transplantation
• Neurodegenerative disease: Characterization of the effect of the protein-amiloide function of bacterial and other items amiloidogene of the gut microbiota on the aggregation of pathological proteins, and the propagation of the pathology of a pattern in the prionic in models of neurodegeneration, in order to identify biomarkers and targets for the molecular to the development of strategies of prevention and treatment tailored to them. in Parkinson's disease on and other neuro-degenerative diseases, thus contributing to the improvement of the approach of having a major impact on your health.
• The regeneration of skeletal muscle in the muscles of normal and distrofici, with the aim of identifying biomarkers for new and potentially more relevant to the progression of the disease to the chronic diseases and genetic disorders.
• The research of epigenetic modifications at the level of the methylation of DNA and modification of post-translation histonelor; bioactive Compounds, natural and that it acts as a modulator epigenetici in chimioprevenție studies in vitro.