Publications Radiobiology

Publications & Patents

  1. Gkikoudi A, Manda G, Beinke C, Giesen U, Al-Qaaod A, Dragnea EM, Dobre M, Neagoe IV, Sangsuwan T, Haghdoost S, Vasilopoulos SN, Triantopoulou S, Georgakopoulou A, Tremi I, Koutsoudaki PN, Havaki S, Gorgoulis VG, Kokkoris M, Krasniqi F, Terzoudi GI, Georgakilas AG. Synergistic Effects of UVB and Ionizing Radiation on Human Non-Malignant Cells: Implications for Ozone Depletion and Secondary Cosmic Radiation Exposure. Biomolecules 2025 Apr, 15(4):536. doi: 10.3390/biom15040536.
  2. Cuadrado A, Cazalla E, Bach A, Bathish B, Naidu SD, DeNicola GM, Dinkova-Kostova AT, Fernández-Ginés R, Grochot-Przeczek A, Hayes JD, Kensler TW, León R, Liby KT, López MG, Manda G, Shivakumar AK, Hakomäki H, Moerland JA, Motohashi H, Rojo AI, Sykiotis GP, Taguchi K, Valverde ÁM, Yamamoto M, Levonen AL. Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases. Redox Biol. 2025 Apr, 81:103569. doi: 10.1016/j.redox.2025.103569.
  1. Burloiu, A.M.; Mihai, D.P.; Manda, G.; Lupuliasa, D.; Neagoe, I.V.; Socoteanu, R.P.; Surcel, M.; Anghelache, L.-I.; Olariu, L.; Gîrd, C.E., Rica Boscencu. In Silico and In Vitro Studies on an Asymmetrical Porphyrin Derivative with Therapeutic Potential in Skin Disorders. Pharmaceuticals, 17(6), 688, 2024
  2. Cristian Funieru, Mihnea Ioan Nicolescu, Cristian Băicuş, Oana Slușanschi, Clara Ilinca Bica, Andreea Moldoveanu, Anca Cristina Perpelea, Adrian Teodor Țandără. Oral Hygiene Profile of Schoolchildren from Bucharest, Romania—How It Can Be Used and Improved for Better Prevention of Oral Diseases. Healthcare 12 (13), 1293, 2024
  3. Mihnea Ioan Nicolescu, Oana Irina Lupu, Raluca Ștefania Georgescu, Mihai Săndulescu, Cristian Funieru. Management of SARS-CoV-2 Prevention Methods in Dental Offices—A Cross-Sectional Study in Bucharest, Romania.Healthcare 12 (12), 1169, 2024
  4. Ultimescu F, Hudita A, Popa DE, Olinca M, Muresean HA, Ceausu M, Stanciu DI, Ginghina O, Galateanu B. Impact of Molecular Profiling on Therapy Management in Breast Cancer. J Clin Med. 2024 Aug 23;13(17):4995
  5. Anca-Stanciu MB, Manu A, Olinca MV, Coroleucă BC, Comandaşu DE, Coroleucă CA, Maier C, Brătilă E. Prognostic implications of immunohistochemistry in patients with endometrial cancer. Romanian Journal of Morphology and Embryology 65.2 (2024): 185
  6. Ardeleanu CM, Olinca MV, Viişoreanu CG, Mureşan HA, Tecuceanu-Vulpe A, Manole G, Gune IE, Gălăţeanu B, Ilie-Petrov AC, Ultimescu F. NGS mutational status on first diagnostic tissue, liquid biopsy and mastectomy in G2-G3 breast cancer. Rom J Morphol Embryol. 2024 Apr-Jun;65(2):195-201
  1. Rusu MC, Mănoiu VS, Nicolescu MI. Pennate myofibrils of the rat temporal muscle. Ann Anat. 2023;249:152096. doi:10.1016/j.aanat.2023.152096
  2. Săndulescu M, Nicolescu MI, Funieru C, Şahin GÖ, Săndulescu O; ESCMID Study Group for Viral Hepatitis (ESGVH). Exposure to Biological Fluids in Dental Practice-Narrative Review on Appropriate Risk Assessment to Guide Post-Exposure Management. 2023;12(7):968. doi:10.3390/pathogens12070968
  3. Funieru C, Tudose DȘ, Dobrică B, Săndulescu M, Popovici IA, Slușanschi EI, Croitoru SM, Vrînceanu D, Bănică B, Nicolescu MI. A New Model of Salivary Pacemaker—A Proof of Concept and First Clinical Use. 2023; 59(9):1647. doi:10.3390/medicina59091647
  4. AM Burloiu, G Manda, D Lupuliasa, RP Socoteanu, DP Mihai, IV Neagoe, LI Anghelache, M Surcel, M Anastasescu, L Olariu, CE Gird, SF Barbuceanu, LFV Ferreira, R Boscencu. Assessment of Some Unsymmetrical Porphyrins as Promising Molecules for Photodynamic Therapy of Cutaneous Disorders. Pharmaceuticals 2024, 17, 62. https://doi.org/10.3390/ph17010062
  5. A Gkikoudi, SA Kalospyros, S Triantopoulou, S Logotheti, V Softa, C Kappas, K Theodorou, EC Laiakis, G Manda, GI Terzoudi, AG Georgakilas. Molecular Biomarkers for Predicting Cancer Patient Radiosensitivity and Radiotoxicity in Clinical Practice. Sci. 2023, 13(23), 12564; https://doi.org/10.3390/app132312564
  6. A Ciobanu, G Manda, I Neagoe, M Barca, C Balalau, EG Turcu, CM Gutu, DE Popa, DL Baconi. The immune status of heroin addicts during treatment with methadone. Farmacia 71 (6), 2023, https://doi.org/10.31925/farmacia.2023.6.9
  7. D Niculae, R Serban, L Chilug, D Niculae, D Cocioabă, MR Cornoiu, A Dinischiotu, I Neagoe, G Manda. Investigation of therapeutic effect, associated hypoxia and antioxidant signaling induced by copper-64 in colon carcinoma. Nuclear Medicine and Biology 126, 108474
  8. R Boscencu, G Manda, G Vasiliu, R Socoteanu, D Lupuleasa, AM Burloiu, IV Neagoe, L Olariu. Preliminary In Vitro Evaluation of Some Porphyrins Using Human Breast Tumor Cells. Letters in Drug Design & Discovery, 20 (8), 1040-1045, DOI:10.2174/1570180819666220318153003
  9. RM Serban, D Niculae, G Manda, I Neagoe, M Dobre, DA Niculae, M Temelie, C Mustaciosu, RA Leonte, LE Chilug, MR Cornoiu, D Cocioaba, M Stan, A Dinischiotu. Modifications in cellular viability, DNA damage and stress responses inflicted in cancer cells by copper-64 ions. Frontiers in Medicine 10, 11978461 https://doi.org/10.3389/fmed.2023.1197846, 2023
  10. DP Mihai, R Boscencu, G Manda, AM Burloiu, G Vasiliu, IV Neagoe, RP Socoteanu, D Lupuliasa. Interaction of Some Asymmetrical Porphyrins with U937 Cell Membranes–In Vitro and In Silico Studies. Molecules 2023 Feb 8;28(4):1640. doi:10.3390/molecules28041640.
  11. R Boscencu, N Radulea, G Manda, IF Machado, RP Socoteanu, D Lupuliasa, AM Burloiu, DP Mihai, LF Vieira Ferreira. Porphyrin Macrocycles: General Properties and Theranostic Potential. Molecules 2023, 28, 1149. https://doi.org/10.3390/molecules28031149
  12. S Bhaumik, M Łazarczyk, N Kubick, P Klimovich, A Gurba, J Paszkiewicz, P Teodorowicz, T Kocki, JO Horbańczuk, G Manda, M Sacharczuk, ME Mickael. Investigation of the Molecular Evolution of Treg Suppression Mechanisms Indicates a Convergent Origin. Curr Issues Mol Biol. 2023 Jan 9;45(1):628-648. doi:10.3390/cimb45010042
  13. Dobre M.; Poenaru R.C.; Niculae A.M.; Vladut C.; Herlea V.; Milanesi E*.; Hinescu M.E. Increased Levels of miR-15b-5p and miR-20b-5p in Pancreatic Ductal Adenocarcinoma with Hepatic Metastases. Genes (Basel). 2023 Aug 2;14(8):1577. doi: 10.3390/genes14081577
  14. Parlatescu I.; Dugan C.; Popescu B.O.; Tovaru S.; Dobre M.; Milanesi E*. Non-Communicable Diseases and Associated Risk Factors in Burning Mouth Syndrome Patients. Medicina (Kaunas). 2023 Nov 27;59(12):2085. doi: 10.3390/medicina59122085
  15. Grosu Ș.-A.; Dobre M.; Milanesi E.*; Hinescu M.E. Blood-Based MicroRNAs in Psychotic Disorders—A Systematic Review. 2023 Sep 14;11(9):2536. doi: 10.3390/biomedicines11092536
  16. Dugan C.; Popescu B.O.; Țovaru S.; Părlătescu I.; Musat I.A.; Dobre M.; Ribigan A.C.; Milanesi E*. Neuropsychological assessment of Romanian burning mouth syndrome patients: stress, depression, sleep disturbance, and verbal fluency impairments. Front Psychol. 2023 May 15;14:1176147. doi: 10.3389/fpsyg.2023.1176147.
  17. Isac T., Droc G., Klimko A., Cotorogea-Simion M., Dobre M., Milanesi E., Cucu N., Balcangiu-Stroescu AE., Iliescu L., Isac S. Epigenetic Modulation in Viral Hepatitis C Infected Patients after Successful Therapy. Biointerface Research in Applied Chemistry. Volume 13, Issue 3, 2023, 213 doi: 10.33263/BRIAC133.213
  18. Mizrahi L.; Choudhary A.; Ofer P.; Goldberg G.; Milanesi E.; Kelsoe J.R.; Gurwitz D.; Alda M.; Gage F.H.; Stern. Immunoglobulin genes expressed in lymphoblastoid cell lines discern and predict lithium response in bipolar disorder patients. Mol Psychiatry. 2023 Oct;28(10):4280-4293. doi: 10.1038/s41380-023-02183-z.
  1. Manda G, Milanesi E, Genc S, Niculite C, Neagoe IV, Tastan B, Dragnea EM, Cuadrado A. Pros and cons of NRF2 activation as adjunctive therapy in rheumatoid arthritis. Free Radical Biology and Medicine. 2022;190:179-201
  2. Cucu I, Nicolescu MI, Busnatu ȘS, Manole CG. Dynamic Involvement of Telocytes in Modulating Multiple Signaling Pathways in Cardiac Cytoarchitecture. Int J Mol Sci. 2022;23(10):5769
  3. Cucos CA, Milanesi E, Dobre M, Musat IA, Manda G, Cuadrado A. Altered Blood and Brain Expression of Inflammation and Redox Genes in Alzheimer’s Disease, Common to APPV717I × TAUP301L Mice and Patients. Int J Mol Sci. 2022;23(10):5799
  4. Ionescu A, Dodi A, Petcu LC, Nicolescu MI. Open Healing: A Minimally Invasive Protocol with Flapless Ridge Preservation in Implant Patients. Biology (Basel). 2022;11(1):142
  5. Mehedintu C, Frincu F, Ionescu OM, Cirstoiu MM, Sajin M, Olinca M, Bratila E, Petca E, Carp-Veliscu A. A Challenging Diagnosis: Placental Mesenchymal Dysplasia-Literature Review and Case Report. Diagnostics (Basel). 2022;12(2):293
  6. Dugan C, Parlatescu I, Dobre M, Pîrvu RE, Milanesi E. Insights on brain functions in burning mouth syndrome. Front Syst Neurosci. 2022;16:975126
  7. Busnatu ȘS, Niculescu AG, Bolocan A, (…), Nicolescu MI, Grumezescu, AM, Jinga V . A Review of Digital Health and Biotelemetry: Modern Approaches towards Personalized Medicine and Remote Health Assessment. J Pers Med. 2022;12(10):1656
  8. Cucos CA, Dobre M, Dragnea EM, Manda G, Milanesi E. Increased MYD88 blood transcript in a mouse model of Alzheimer’s disease. BMC Neurosci. 2022;23(1):13
  9. Rusu MC, Vrapciu AD, Nicolescu MI, (…), Mănoiu VS, Hostiuc S. Extruded Nucleoli of Human Dental Pulp Cells. Medicina (Kaunas). 2022;58(2):260
  10. Rusu MC, Nicolescu MI, Vrapciu AD. Evidence of lymphatics in the rat eye retina. Ann Anat. 2022; 244:151987
  11. Cucos CA, Cracana I, Dobre M, Surcel M, Popescu BO, Tudose C, Spiru L, Manda G, Niculescu G, Milanesi E. Sulfiredoxin-1 blood mRNA expression levels negatively correlate with hippocampal atrophy and cognitive decline . F1000Res. 2022; 11:114
  12. Berceanu C, Cernea N, Căpitănescu RG, Comănescu AC, Paitici S, Rotar IC,Bohîlţea RE, Olinca MV. Endometrial polyps. Rom J Morphol Embryol. 2022;63(2):323-334
  1. Milanesi E, Manda G, Dobre M, Codrici E, Neagoe IV, Popescu BO, Bajenaru OA, Spiru L, Tudose C, Prada GI, Davidescu EI, Piñol-Ripoll G, Cuadrado A. Distinctive Under-Expression Profile of Inflammatory and Redox Genes in the Blood of Elderly Patients with Cardiovascular Disease. J Inflamm Res. 2021, 14:429-442
  2. Milanesi, Maria Dobre, Cătălina Anca Cucoș, Ana I. Rojo, José Jiménez-Villegas, Estibaliz Capetillo-Zarate, Carlos Matute, Gerard Piñol-Ripoll, Gina Manda, Antonio Cuadrado. Whole Blood Expression Pattern of Inflammation and Redox Genes in Mild Alzheimer’s Disease. J Inflamm Res. 2021, 14: 6085-6102
  3. Dobre M.,Herlea V., Vlăduţ C., Ciocîrlan M., Balaban V.D.,Constantinescu G., Diculescu M., Milanesi E. Dysregulation of miRNAs targeting the igf-1r pathway in pancreatic ductal adenocarcinoma. 2021, 10(8),1856
  4. Maria Dobre, Alessandro Salvi, Iulia Andreea Pelisenco, Florina Vasilescu, Giuseppina De Petro, Vlad Herlea, Elena Milanesi. Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer. Frontiers in Oncology. 2021, 11, 697409
  5. Elena Milanesi, Cătălina Anca Cucos, Jordi A Matias-Guiu, Gerard Piñol-Ripoll, Gina Manda, Maria Dobre, Antonio Cuadrado. Reduced blood RGS2 expression in mild cognitive impairment patients. Frontiers in Aging Neuroscience 2021, 13: 738244
  6. Maria Dobre, Rica Boscencu, Ionela Victoria Neagoe, Mihaela Surcel, Elena Milanesi, Gina Manda. Insight into the Web of Stress Responses Triggered at Gene Expression Level by Porphyrin-PDT in HT29 Human Colon Carcinoma Cells. Pharmaceutics 2021, 13(7): 1032
  7. Radu Anton Leonte, Livia Elena Chilug, Radu Șerban, Cosmin Mustăciosu, Alina Raicu, Gina Manda, Dana Niculae. Preparation and Preliminary Evaluation of Neurotensin Radiolabelled with 68Ga and 177Lu as Potential Theranostic Agent for Colon Cancer. Pharmaceutics 2021, 13(4): 506
  8. Radu Petre Socoteanu, Rica Boscencu, Gina Manda, Mihai Anastasescu, Ionela Victoria Neagoe, Isabel Ferreira Machado, Octavian Dinca, Alexandru Bucur, Luis Filipe Vieira Ferreira. Morphologic evaluation of some promising A3B porphyrinic type compounds designed for theranostic applications in cancer. Chemical Physics 2021, 544: 111115
  9. Cristian George Tieranu, Andrei Ovidiu Olteanu, Carmen Monica Preda, Nicolae Bacalbasa, Elena Milanesi, Maria Dobre, Ioana Tieranu, Teodora Ecaterina Manuc, Artsiom Klimko, Gabriel Becheanu, Elena Mirela Ionescu. Mucosal gene expression profile of stricturing Crohn’s disease: A preliminary study. Experimental and therapeutic Medicine 2021, Article number: 149. https://doi.org/10.3892/etm.2021.11072
  10. Maier Calina; Poteca Anca;  Olinca Maria;  Vladareanu Radu;  Bratila Elvira. Placental mesenchymal dysplasia and maternal factor V Leiden: Accountable for severe early-onset intrauterine growth restriction? European Journal of Obstetrics & Gynecology and Reproductive Biology, DOI: 10.1016/J.EJOGRB.2021.09.014
  1. Livia Elena Chilug, Dana Niculae, Radu Anton Leonte, Alexandrina Nan, Rodica Turcu, Cosmin Mustaciosu, Radu Marian Serban, Vasile Lavric, Gina Manda. Preclinical Evaluation of NHS-Activated Gold Nanoparticles Functionalized with Bombesin or Neurotensin-Like Peptides for Targeting Colon and Prostate Tumours. Molecules 2020, 25: 3363.
  2. Antonio Cuadrado, Marta Pajares, Cristina Benito, José Jiménez-Villegas, Maribel Escoll, Raquel Fernández-Ginés, Angel J. Garcia Yagüe, Diego Lastra, Gina Manda, Ana I. Rojo, Albena T. Dinkova-Kostova. Can Activation of NRF2 Be a Strategy against COVID-19? Trends in Pharmacological Sciences, 1738, 22 July 2020.
  3. Marta Pajares, Ana I. Rojo, Gina Manda, Lisardo Boscá, Antonio Cuadrado. Inflammation in Parkinson’s Disease: Mechanisms and Therapeutic Implications. Cells 2020, 9(7), 1687.
  4. Norwin Kubick, Marta Pajares, Ioana Enache, Gina Manda, Michel-Edwar Mickael. Repurposing Zileuton as a Depression Drug Using an AI and In Vitro Approach. Molecules 2020, 25(9): 2155.
  5. Funieru C, Obagiu IA, Oancea R, Dobrica B, Sfeatcu RI, Nicolescu MI. Erosive Potential of Three Different Beverages on Human Enamel and Dentine: An in vitro Study. Revista de Chimie, 71(3):192-196, 2020.
  6. Nicolescu MI, Rusu MC, Voinea LM, Vrapciu AD, Bâră R. Lymphatic lacunae of the human eye conjunctiva embedded within a stroma containing CD34+ telocytes. Journal of Cellular and Molecular Medicine, 24(15):8871-8875, 2020.
  1. Gina Manda, Cristian Postolache, Ionela Victoria Neagoe, Andreea Csolti, Elena Milanesi, Maria Dobre. The expression profile of redox genes in human monocytes exposed in-vitro to γ radiation. Radiation Physics and Chemistry 2019, 170: 108634.
  2. Gina Manda, Ana I. Rojo, Elena Martínez-Klimova , José Pedraza-Chaverri, Antonio Cuadrado. Nordihydroguaiaretic acid: from herbal medicine to clinical development for cancer and chronic diseases. Frontiers Pharmacology 2019, 11:151.
  3. Alina-Andreea Zimta, Vlad Schitcu, Eugen Gurzau, Crina Stavaru, Gina Manda, Stefan Szedlacsek, Ioana Berindan-Neagoe. Biological and molecular modifications induced by cadmium and arsenic during breast and prostate cancer development. Environmental Research 2019, 178: 108700, https://doi.org/10.1016/j.envres.2019.108700.
  4. Asavei T, Bobeica M, Nastasa V, Manda G, et al. Laser-driven radiation: Biomarkers for molecular imaging of high dose-rate effects. Medical Physics 2019, 46(10): e726-e734.
  5. Robledinos-Anton N, Fernandez-Gines R, Manda G, Cuadrado A. Activators and inhibitors of NRF2: A review of their potential for clinical development. Oxid Med Cell Longev 2019, 2019:9372182.
  6. Radu Albulescu, Adrian-Claudiu Popa, Ana-Maria Enciu, Lucian Albulescu, Maria Dudau, Ionela Daniela Popescu, Simona Mihai, Elena Codrici, Sevinci Pop, Andreea-Roxana Lupu, George E Stan, Gina Manda, Cristiana Tanase. Comprehensive In Vitro Testing of Calcium Phosphate-Based Bioceramics with Orthopedic and Dentistry Applications. Materials 2019, 12(22): 3704.
  7. Natalia Radulea, Rica Boscencu, Radu Socoteanu, Gina Manda, Ionela Victoria Neagoe. The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells. Revista de Chimie 2019, 70(4): 1288-1292.
  8. Gina Manda, Mihail Eugen Hinescu, Ionela Victoria Neagoe, Luis Filipe Vieira Ferreira, Rica Boscencu, Paul Vasos, Selma Huveyda Basaga, Antonio Cuadrado. Emerging Therapeutic Targets in Oncologic Photodynamic Therapy. Current Pharmaceutical Design 2019, 24(44): 5268-5295.
  9. Ionescu A, Dodi A, Panagopoulos V, Nicolescu MI, Mihai AT, Tanase G, Vlasceanu D. Biomechanical consequences of dental implants inserted in augmented alveolar ridges – a comparative study between tissue-level and bone-level implants: finite elements analysis. Romanian Journal of Oral Rehabilitation, 11(1):82-88, 2019.
  10. Rusu MC, Nicolescu MI, Jianu AM, Manoiu VS, Ilie C, Dinca D. The ultrastructural anatomy of the nuclear envelope in the masseter muscle indicates its role in the metabolism of the intracellular Ca++. Annals of Anatomy-Anatomischer Anzeiger, 224:117-123, 2019.
  11. Manole CG, Marinescu BG, Marta D, Nicolescu MI. Areas of cartilaginous and osseous metaplasia after experimental myocardial infarction in rats. The Anatomical Record, 302(6):947-953, 2019.
  12. Istrate-Ofiţeru AM, Pîrvan IC, Pirici D, Roşu GC, Niculescu M, Berceanu S, Manolea MM, Comănescu MV, Voicu NL, Iovan L, Vasile MM, Căpitănescu RG, Diţescu D, Mogoantă L, Berceanu C. Triple immunohistochemistry for assessing the inflammatory, vascular and progression of adenomyosis. Rom J Morphol Embryol, 60(2):419-428, 2019.
  1. Panait ME, Chilug L, Negoita V, Busca A, Manda G, Niculae D, Dumitru M, Gruia MI. Biological effects induced by 68Ga – conjugated peptides in human and rodent tumor cell lines. Molecular Imaging and Biology 2018, 25: 979–987.
  2. Boscencu R, Socoteanu RP, Manda G et al. New A3B porphyrins as potential candidates for theranostic. Synthesis and photochemical behaviour. Dyes and Pigments 2018, 160: 410-417.
  3. Codeanu C, Popescu CC, Mogosan C, Enache L, Manda G, Berghea F, Groseanu L, Predeteanu D. Targeting interleukin 17 in the treatment of rheumatoid arthritis. Farmacia 2018, 66(3): 390-398.
  4. Antonio Cuadrado, Gina Manda, Ahmed Hassan, et al. Transcription factor NRF2 as a therapeutic target for chronic diseases: a systems medicine approach. Pharmacological Reviews 2018, 70(2):348-383.
  5. Pietro Ghezzi, Luciano Floridi, Diana Boraschi, Antonio Cuadrado, Gina Manda, Snezana Levic, Fulvio D’Acquisto, Alice Hamilton, Toby J Athersuch, Liza Selley. Oxidative stress and inflammation induced by environmental and psychological stressors: A biomarker perspective, Antioxidants & redox signaling 2018, 28(9): 852-872.
  6. Cionca FL, Dobre M, Dobrea CM, Iosif CI, Comănescu MV, ArdeleanuMutational status of KRAS and MMR genes in a series of colorectal carcinoma cases. Rom J Morphol Embryol, 59(1):121-129, 2018.
  7. Corici OA, Tanasie CA, Alexandru DO, Florescu MC, Comănescu MV, Kamal KC, Ţenea-Cojan TŞ, Iancău M, Dinescu A morpho-functional study using PEP/LVET ratio and global longitudinal strain in patients with dilated cardiomyopathy. Rom J Morphol Embryol, 59(1):93-103, 2018.
  1. Burns JS, Manda G. Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance, International Journal of Molecular Science 2017, 18(12):2755.
  2. Rica Boscencu, Gina Manda, Natalia Radulea, Radu Petre Socoteanu, Laura Cristina Ceafalan, Ionela Victoria Neagoe, Isabel Ferreira Machado, Selma Huveyda Basaga, Luís Filipe Vieira Ferreira. Studies on the Synthesis, Photophysical and Biological Evaluation of Some Unsymmetrical Meso-Tetrasubstituted Phenyl Porphyrins, Molecules 2017, 22(11): 1815.
  3. Chilug LE, Leonte RA, Barbinte Patrascu ME, Ion AC, Tuta CS, Raicu A, Manda G, Niculae D. In vitro binding kinetics study of gold nanoparticles functionalized with 68Ga-DOTA conjugated peptides. J Radioanal Nucl Chem 2017, 3(2):1485-1493.
  4. Barca M, Manda G, Ciobanu AM, Balalau C, Lupuleasa D, Traian G, Dragomiroiu GTAB, Pop A, Popa DE, Baconi DL. Immunomodulatory effects of methadone following methotrexate therapy in a rat model of arthritis, Farmacia 2017, 65(3):423-428.
  1. Asavei T, Tomut M, Bobeica M, Aogaki S, Cernaianu MO, Ganciu M, Kara S, Manda G, et al. Materials in extreme environments for energy, accelerators and space applications at ELI-NP, Romanian Reports in Physics 2016, 68(Suppl): S275–S347.
  2. Checheriţă IA, Manda G, Hinescu ME, Peride I, Niculae A, Bilha S, Gramaticu A, Voroneanu L, Covic A. New molecular insights in diabetic nephropathy. International Urology and Nephrology 2016, 48(3): 373-387.
  3. Nicolescu MI. Telocytes in Exocrine Glands Stroma. Advances in Experimental Medicine and Biologies, 913:163-176, 2016.
  4. Calenic B, Greabu M, Caruntu C, Nicolescu MI, Moraru, Surdu-Bob CC, Badulescu M, Anghel A, Logofatu C, Boda D.Oral keratinocyte stem cells behavior on diamond like carbon films. Romanian Biotechnological Letters, 21(5):11914-11922, 2016.
  1. Dumitrache F, Morjan IG, Fleaca CI, Badoi A, Manda G, Pop S, Marta DS, et.al. Highly magnetic Fe2O3 nanoparticles synthesized by laser pyrolysis used for biological and heat transfer applications. Applied Surface Science 2015, 336: 297–303.
  2. Socoteanu R, Manda G, Boscencu R, Vasiliu G, Anabela Sousa Oliveira. Synthesis, spectral analysis and preliminary in vitro evaluation of some tetrapyrrolic complexes with 3d metal ions. Molecules 2015, 20(9): 15488-15499, doi:10.3390/molecules200915488.
  3. Manda G, Isvoranu G, Comanescu MV, Manea A, Debelec Butuner B, Korkmaz KS. The redox biology network in cancer pathophysiology and therapeutics. Redox Biology 2015, 5: 347-357.
  4. Manea SA, Constantin A, Manda G, Sasson S, Manea A. Regulation of Nox enzymes expression in vascular pathophysiology: Focusing on transcription factors and epigenetic mechanisms. Redox Biology 2015, 5: 358-366.
  5. Manda G, Mocanu MA, Marin DE, Taranu I. Dual Effects Exerted in Vitro by Micromolar Concentrations of Deoxynivalenol on Undifferentiated Caco-2 Cells. Toxins 2015, 7(2), 593-603.
  6. Manda G, Checherita AI, Comanescu MV, Hinescu ME. Redox Signaling in Diabetic Nephropathy: Hypertrophy versus Death Choices in Mesangial Cells and Podocytes. Mediators of Inflammation 2015, 2015, Article ID 604208.
  7. Rusu MC, Poalelungi CV, Vrapciu AD, Nicolescu MI*, Hostiuc S, Mogoanta L, Taranu T. Endocardial Tip Cells in the Human Embryo – Facts and Hypotheses. PLoS One, 10(1): e0115853, 2015.
  8. Rusu MC, Hostiuc S, Dermengiu D, Nicolescu MI, Jianu AM. STRO-1 positive pulmonary valve stem cells: preliminary report. Romanian Journal of Legal Medicine. 23(1):1-4, 2015.
  1. Margina D, Ilie M, Manda G, Neagoe I, Danciulescu-Miulescu R, Purdel CD, Gradinaru D. In vitro effects of prolonged exposure to quercetin and epigallocatechin gallate of the peripheral blood mononuclear cell membrane. Cellular and Molecular Biology Letters 2014, 19: 542-560.
  1. Margina D, Gradinaru D, Manda G, Neagoe I, Ilie M. Membranar effects exerted in vitro by polyphenols – quercetin, epigallocatechin gallate and curcumin – on HUVEC and Jurkat cells, relevant for diabetes mellitus. Food Chem Toxicol, 61:86-93, 2013, pii: S0278-6915(13)00155-5.

Nechifor MT, Niculiţe CM, Urs AO, Regalia T, Mocanu M, Popescu A, Manda G, Dinu D, Leabu M. UVA Irradiation of Dysplastic Keratinocytes: Oxidative Damage versus Antioxidant Defense. Int. J. Mol. Sci, 13, 16718-16736, 2012

  1. Rusu MC, Mirancea N, Manoiu VS, Valcu M, Nicolescu MI, Paduraru D. Skin telocytes. Annals of Anatomy, 194(4):359-367, 2012.
  2. Nicolescu MI, A Bucur, O Dinca, MC Rusu, Popescu LM. Telocytes in Parotid Glands.The Anatomical Record, 295(3):378-385, 2012.
  3. Nicolescu MI, Popescu LM. Telocytes in the interstitium of human exocrine pancreas: ultrastructural evidence. Pancreas, 41(6):949-956, 2012.

Rusu MC, Nicolescu MI, Jianu AM, Lighezan R, Manoiu VS, Paduraru D. Esophageal telocytes and hybrid morphologies. Cell Biology International, 36(12):1079-1088, 2012

  1. Marin DE, Taranu I, Burlacu R, Manda G, Motiu M, Neagoe I, Dragomir C, Stancu M, Calin L. Effects of zearalenone and its derivatives on porcine immune response. Toxicology In Vitro. 25(8):1981-1988, 2011.
  2. Taranu I, Daniela E. Marin DE, Manda G, Motiu M, Ionela Neagoe I, Cristina Tabuc C, Stancu M, Olteanu M. Assessment of the potential of a boron–fructose additive in counteracting the toxic effect of Fusarium mycotoxins. Br J Nutrition, 106(3): 398-407, 2011.
  3. Enciu AM, Nicolescu MI, Manole CG, Muresanu DF, Popescu LM, Popescu BO. Neuroregeneration in neurodegenerative disorders. BMC Neurology, 11:75, 2011.
  1. Rica Boscencu, Mihaela Ilie, Radu Socoteanu, Anabela Sousa Oliveira, Carolina

Constantin, Monica Neagu, Gina Manda, Luis Filipe Vieira Ferreira. Synthesis, Basic Spectral and Biological Evaluation of Some Copper (II) Mesoporphyrinic Complexes. Molecules, 15(5), 3731-3743, 2010.

  1. Lidia Matei, Ionela Neagoe, C. Postolache, C.V. Tanase, G. Bubueanu, Gina Manda. In vitro and in vivo Radiometrical Studies For Evaluation of New Nucleoside Analogue Behavior. Label Compd. Radiopharm. 53: 294-299, 2010.
  2. Suciu L, Popescu LM, Gherghiceanu M, Regalia T, Nicolescu MI, Hinescu ME, Faussone-Pellegrini MS. Telocytes in human term placenta: morphology and phenotype. Cells Tissues Organs, 192(5): 325-339, 2010.
  3. Popescu LM, Manole CG, Gherghiceanu M, Ardelean A, Nicolescu MI, Hinescu ME, Kostin S. Telocytes in human epicardium. Journal of Cellular and Molecular Medicine, 14(8): 2085-2093, 2010.
  4. Suciu L, Nicolescu MI, Popescu LM. Cardiac telocytes: serial dynamic images in cell culture. Journal of Cellular and Molecular Medicine, 14(11): 2687-2692, 2010.
  1. Gina Manda, Marina Tamara Nechifor, Teodora-Monica Neagu. Reactive Oxygen Species, Cancer and Anti-Cancer Therapies. Current Chemical Biology, 3(1): 342-366, 2009.
  2. Gina Manda, Monica Neagu, Carolina Constantin, Ionela Neagoe, Catalin Codreanu. Preliminary study on the immunologic background of good clinical outcome in rheumatoid arthritis patients after one-month therapy with leflunomide. Rheumathology International, 29(8): 937-946, 2009.
  3. Tanase CP, Dima S, Mihai M, Raducan E, Nicolescu MI, Albulescu L, Voiculescu B, Dumitrascu T, Cruceru LM, Leabu M, Popescu I, Hinescu ME. Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal adenocarcinoma. Journal of Molecular Histology, 40(1):23-29, 2009.

 

  • OSIM patent RO132752 (B1)/2023 Derivat porfirinic pentru utilizare în teranostică – authors: Boscencu R, Manda G, Socoteanu RP, Hinescu ME, Neagoe IV, Olariu L, Dumitriu B, published in RO-BOPI /29.11.2023

  • OSIM patent RO137442 (A0)/2023 Porphyrin compound with fluorescent marker potential in dermato-oncology -– authors: Burloiu AM, Manda G, Boscencu R, Neagoe IV, Lupuliasa D, Surcel M, Olariu L, Mihai DP, published in RO-BOPI /30.05.2023

  • OSIM patent RO137221 (A0)/2023 Magnetic nanostructures based on neurotensin-peptide-functionalized polymer, labeled with radioisotope 64Cu for diagnostic in oncological pathology – Authors:  Nan AE, Turcu PR, Manda G, Neagoe IV, Chilug EL, Leonte RA, Niculae D, Duşman RD, published in RO-BOPI /30.01.2023

  • OSIM patent RO135597 (A0)/2022 Method of testing and reasearching the effects exerted at the cellular level by the tritiated water, using expression changes of stress genes – authors:  Manda G, Dobre M, Neagoe IV, published in RO-BOPI /30.03.20

  • OSIM patent RO135289 (A0)/2021 Method of evaluation of behavioural disinhibition in an animal model of Alzheimer’s disease (app/tau transgenic rats), using eight-arm radial maze – authors: Cucoş CA, Milanesi E, Dobre M, Anghelache II, Cuadrado AP, Manda G, published in RO-BOPI /29.11.2021

  • OSIM patent RO134431 (A0)/2020 Tetrapyrrole derivative meant for antitumor photodynamic therapy and process for preparing the same – authors: Boscencu R, Manda G, Olariu L, Neagoe Iv, Socoteanu RP, Hinescu ME, Vieira Ferreira LF, Cuadrado A, Basaga SH, published in RO-BOPI /30.09.2020

  • OSIM patent 131946/2019 Tetrapyrrolic compound with theranostic applications and obtaining process – authors: Boscencu R, Manda G, Socoteanu RP, Hinescu ME, Radulea N, Neagoe IV, Ferreira LFV.
  • OSIM patent 01030/2017 Porphyrin derivative for theranostic use – authors: Boscencu R, Manda G, Socoteanu RP, Hinescu ME, Neagoe I, Olariu L, Dumitriu B.
  • OSIM patent 125018 B1/2015 Biofunctionalized porphyrinic compound – authors: Socoteanu R, Boscencu R, Nacea V, Constantin C, Manda G, Neagu M, Ilie M, Oliveira AS, Ferreira LFV, published in RO-BOPI 4/30.04.2015
  • OSIM patent 126761 B1/2014 Asymmetrically substituted porphyrinic compound, as a photosensitizing agent, used in cancer diagnosis and its preparation process – authors: Boscencu R, Socoteanu R, Constantin C, Neagu M, Manda G, Ilie M, Nacea V, Gird CE, Oliveira AS, Ferreira LFV.
  • OSIM patent 128433 A2/2013 Procedure for the identification and dosing by HPLC of leflunomide in the patients’ blood – authors: Negrei C, Baconi D, Margină D, Bălănescu A, Berghea F, Ilie M, Manda G, published in RO-BOPI 5/30.05.2013
  • OSIM patent 123419 B1/2012 Asymmetrically substituted tetrapyrrolic compound, obtaining process and biological evaluation at cellular level – authors: Boscencu R, Socoteanu R, Nacea V, Constantin C, Manda G, Neagu M, Ilie M, Baconi DL, Oliveira AS, Ferreira LFV, published in RO-BOPI 3/30.03.2012
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