The Program's Nucleus 2023-2026
Molecular mechanisms in non-communicable diseases in major cancer in the pathology of degenerative disease of the size of the gene in the immune
Acronym: MEMOGEN
Program Director: Prof. Dr Mihail Eugen Hinescu
The objectives of the program:
Ob1. The identification of the mechanisms and molecular determinants in the pathogenesis of non-communicable diseases, the impact of diagnosis and treatment
Ob2. The identification and/or validation of targets for molecular cancer in order to adapt the therapeutic strategy
Ob3. The maintenance and improvement of the human resources senior specialist in PATHOLOGY, "Victor Babeş"
Ob4. The maintenance and development of the infrastructure of the CD of INCD "Victor Babeş"
OBJECTIVE 1
Project 1: advanced Strategy for the exploration of the signatures of the molecular impact of diagnosis and therapy in epileptic encephalopathies of children
Project 2: the Sarcopenia-associated neurodegenerative diseases: the definition of the molecular basis of cross-linking on the axis of the brain-to-striated muscle in order to identify prognostic factors and therapeutic targets
Project 3: the Role of the caveolinei-1 amyloidosis, vascular associated with the aging process
Proiect 4: Triada funcțională în psoriazisul experimental murin: sistem imun – piele
OBJECTIVE 2
Project 5: The area to be mediated by the lncRNA – targeted therapy in pancreatic cancer
Project 6: A therapeutic combination based on the transfer adopted by the cells and NK-cells, and an inhibitor of TGFBRI/II melanoma, metastatic
Project 7: Approaches to the molecular 3D model (sferoizi s) edited a gene by the method of CRISPR/Cas9 in the development of solutions for personalized medicine in cancer
Project 8: Genes of the stress response targets for therapeutic radiotherapy and photodynamic therapy of carcinoma of the colon
Project components financed
ID | Title | Project lead |
Objective 1. The identification of the mechanisms and molecular determinants in the pathogenesis of non-communicable diseases, the impact of diagnosis and treatment | ||
PN 23.16.01.01 | The role of the caveolinei-1 amyloidosis, vascular associated with the aging process | CSI Dr. Mihaela Gherghiceanu, |
PN 23.16.01.02 | Laura Cristina-Ceafalan | |
PN 23.16.01.03 | Triada funcțională în psoriazisul experimental murin: sistem imun – piele – intestin | Carolina Constantin |
Objective 2. The identification and/or validation of targets for molecular cancer in order to adapt the therapeutic strategy | ||
PN 23.16.02.01 | Gina Manda | |
PN 23.16.02.02 | Dr Gheorghita Isvoranu | |
PN 23.16.02.03 | Codrici Elena | |
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