Book Chatpers & Publications



Stan, D.; Codrici, E.; Enciu, A.-M.; Olewnik-Kruszkowska, E.; Gavril, G.; Ruta, L.L.; Moldovan, C.; Brincoveanu, O.; Bocancia-Mateescu, L.-A.; Mirica, A.-C.; et al. Exploring the Impact of Alginate—PVA Ratio and the Addition of Bioactive Substances on the Performance of Hybrid Hydrogel Membranes as Potential Wound DressingsGels 20239, 476.


Surcel, M.; Constantin, C.; Munteanu, A.N.; Costea, D.A.; Isvoranu, G.; Codrici, E.; Popescu, I.D.; Tănase, C.; Ibram, A.; Neagu, M. Immune Portrayal of a New Therapy Targeting Microbiota in an Animal Model of Psoriasis. J. Pers. Med. 202313, 1556.


Stan, D.; Ruta, L.L.; Bocancia-Mateescu, L.-A.; Mirica, A.-C.; Stan, D.; Micutz, M.; Brincoveanu, O.; Enciu, A.-M.; Codrici, E.; Popescu, I.D.; et al. Formulation and Comprehensive Evaluation of Biohybrid Hydrogel Membranes Containing Doxycycline or Silver NanoparticlesPharmaceutics 202315, 2696.



Preda, P.; Enciu, A.-M.; Adiaconita, B.; Mihalache, I.; Craciun, G.; Boldeiu, A.; Aricov, L.; Romanitan, C.; Stan, D.; Marculescu, C.; et al. New Amorphous Hydrogels with Proliferative Properties as Potential Tools in Wound Healing. Gels 20228, 604.

Dobri, A.-M.; Codrici, E.; Popescu, I.-D.; Albulescu, L.; Fertig, E.T.; Enciu, A.-M.; Tanase, C.; Hinescu, M.E. Low-Concentrations of Fatty Acids Induce an Early Increase in IL-8 Levels in Normal Human Astrocytes. Metabolites 202212, 329.

Caruntu, A.; Scheau, C.; Codrici, E.; Popescu, I.D.; Calenic, B.; Caruntu, C.; Tanase, C. The Assessment of Serum Cytokines in Oral Squamous Cell Carcinoma Patients: An Observational Prospective Controlled StudyJ. Clin. Med. 202211, 5398.

Caruntu, A.; Moraru, L.; Ciubotaru, D.A.; Tanase, C.; Scheau, C.; Caruntu, C. Assessment of Serum Urea, Creatinine and Uric Acid in Oral CancerJ. Clin. Med. 202211, 3459.





Tanase, C.; Enciu, A.M.; Codrici, E.; Popescu, I.D.; Dudau, M.; Dobri, A.M.; Pop, S.; Mihai, S.; Gheorghișan-Gălățeanu, A.-A.; Hinescu, M.E. Fatty Acids, CD36, Thrombospondin-1, and CD47 in Glioblastoma: Together and/or Separately? Int. J. Mol. Sci. 202223, 604.

Codrici E, Popescu ID, Tanase C, Enciu AM. Friends with Benefits: Chemokines, Glioblastoma-Associated Microglia/Macrophages, and Tumor Microenvironment. Int J Mol Sci. 2022;23(5):2509. Published 2022 Feb

 DOI: 10.3390/ijms23052509




A Review on COVID-19 and Diabetes Mellitus: Unravelling the Hypotheses that Worsen the Prognosis

Radu Albulescu; Simona Olimpia Dima; Ioana Raluca Florea; Daniela Lixandru; Andreea Madalina Serban; Veronica Madalina Aspritoiu; Cristiana Tanase; Irinel Popescu; Sarah Ferber

New Frontiers in Medicine and Medical Research Vol. 5, 6 August 2021, Page 92-108




Complex Interaction Among Immune, Inflammatory, and Carcinogenic Mechanisms in the Head and Neck Squamous Cell Carcinoma

Ana Caruntu , Cristian Scheau , Mircea Tampa , Simona Roxana Georgescu, Constantin Caruntu ,and Cristiana Tanase

Adv Exp Med Biol – Clinical and Experimental Biomedicine





Distinctive Under-Expression Profile of Inflammatory and Redox Genes in the Blood of Elderly Patients with Cardiovascular Disease


Milanesi E, Manda G, Dobre M, Codrici E, Neagoe IV, Popescu BO, Bajenaru OA, Spiru L, Tudose C, Prada GI, Davidescu EI, Piñol-Ripoll G, Cuadrado A

Journal of Inflammation Research. 2021:14 1–14



A Fatty Acid Fraction Purified From Sea Buckthorn Seed Oil Has Regenerative Properties on Normal Skin Cells

Ionela Daniela Popescu, Lucian Albulescu, Nicoleta Constantin, Iulia Cucolea, Teodor Costache, Dan Rambu, Ana-Maria Enciu, Mihail E. Hinescu and Cristiana Tanase

Front. Pharmacol., 08 October 2021

Volume 12 – 2021 |


Independent and complementary bio-functional effects of CuO and Ga2O3 incorporated as therapeutic agents in silica- and phosphatebased bioactive glasses

  1. Tite a, A.C. Popa a, B.W. Stuart b, H.R. Fernandes c, I.M. Chirica a, G.A. Lungu a,
  2. Macovei a, C. Bartha a, L. Albulescu d, C. Tanase d, S. Nita e, N. Rusu e, D.M. Grant b,

J.M.F. Ferreira c, G.E. Stan

Journal of Materiomics 8 (2022) 893e905



Chirică, I.M.; Enciu, A.-M.; Tite, T.; Dudău, M.; Albulescu, L.; Iconaru, S.L.; Predoi, D.; Pasuk, I.; Enculescu, M.; Radu, C.; et al. The Physico-Chemical Properties and Exploratory Real-Time Cell Analysis of Hydroxyapatite Nanopowders Substituted with Ce, Mg, Sr, and Zn (0.5–5 at.%). Materials 202114, 3808.


Dudau M, Vilceanu AC, Codrici E, et al. Sea-Buckthorn Seed Oil Induces Proliferation of both Normal and Dysplastic Keratinocytes in Basal Conditions and under UVA Irradiation. J Pers Med. 2021;11(4):278. Published 2021 Apr 7. doi:10.3390/jpm11040278




Wound healing applications of creams and “smart” hydrogels

Diana Stan | Cristiana Tanase | Marioara Avram1 | Roxana Apetrei| Nicolae-Bogdan

Mincu| Andreea Lorena Mateescu| Dana Stan.

Accepted: 15 May 2021

DOI: 10.1111/exd.14396


Natural Compounds With Antimicrobial and Antiviral Effect and Nanocarriers Used for Their Transportation. Stan D, Enciu AM, Mateescu AL, et al.  Front Pharmacol. 2021;12:723233. Published 2021 Sep 6. doi:10.3389/fphar.2021.723233



Fatty Acids, CD36, Thrombospondin-1, and CD47 in Glioblastoma: Together and/or Separately?

Tanase C, Enciu AM, Codrici E, et al. Int J Mol Sci. 2022;23(2):604. Published 2022 Jan 6. doi:10.3390/ijms23020604


The Hidden Treasures of Preoperative Blood Assessment in Oral Cancer: A Potential Source of Biomarkers

Caruntu A, Moraru L, Lupu M, Taubner L, Caruntu C, Tanase C. Cancers (Basel). 2021;13(17):4475. Published 2021 Sep 5. DOI: 10.3390/cancers13174475



  1. Tanase C, Gheorghisan-Galateanu AA, Popescu ID, Mihai S, Codrici E, Albulescu R, Hinescu ME, CD36 and CD97 in Pancreatic Cancer versus Other Malignancies, Int J Mol Sci.; 21(16): 5656, 2020

DOI: 10.3390/ijms21165656


  1. Lupu MA, Gradisteanu Pircalabioru G, Chifiriuc MC, Albulescu R, Tanase C, Beneficial effects of food supplements based on hydrolyzed collagen for skin care (Review), Exp Ther Med.;20(1):12-17, 2020

DOI: 10.3892/etm.2019.8342.


  1. Duda DG, Dima SO, Cucu D, Sorop A, Klein S, Ancukiewicz M, Kitahara S, Iacob S, Bacalbasa N, Tomescu D, Herlea V, Tanase C, Croitoru A, Popescu I, Potential Circulating Biomarkers of Recurrence after Hepatic Resection or Liver Transplantation in Hepatocellular Carcinoma Patients, Cancers (Basel); 12(5):1275, 2020

DOI: 10.3390/cancers12051275.

  1. Albulescu R, Popa AC, Enciu AM, Albulescu L, Dudau M, Popescu ID, Mihai S, Codrici E, Pop S, Lupu AR, Stan GE, Manda G, Tanase C, Comprehensive In Vitro Testing of Calcium Phosphate-Based Bioceramics with Orthopedic and Dentistry Applications, Materials (Basel),12(22):3704, 2019

DOI: 10.3390/ma12223704.

  1. Mihai S, Codrici E, Popescu ID, Enciu AM, Rusu E, Zilisteanu D, Necula LG, Anton G, Tanase C Inflammation-Related Patterns in the Clinical Staging and Severity Assessment of Chronic Kidney Disease, Disease Markers; ID:1814304, 2019

DOI: 10.1155/2019/1814304.


  1. Niculite CM, Enciu AM, Hinescu ME, CD 36: Focus on Epigenetic and Post-Transcriptional Regulation.

Frontiers in Genetics, 10:680, 2019

DOI: 10.3389/fgene.2019.00680

  1. Tanase C, Popescu ID, Enciu AM, Gheorghisan-Galateanu AA, Codrici E, Mihai S, Albulescu L, Necula L, R Albulescu, Angiogenesis in cutaneous T-cell lymphoma – proteomic approaches, Oncology Letters, 17(5):4060-4067, 2019.

DOI: 10.3892/ol.2018.9734.


  1. Ionescu AM, Ilie MA, Chitu V, Razvan A, Lixandru D, Tanase C, Boda D, Caruntu C, Zurac S, In vivo Diagnosis of Primary Cutaneous Amyloidosis-the Role of Reflectance Confocal Microscopy, Diagnostics (Basel); 9(3):66, 2019

DOI: 10.3390/diagnostics9030066.


  1. Popa ML, Popa AC, Tanase C, Gheorghisan-Galateanu AA, Acanthosis nigricans: To be or not to be afraid, Oncology Letters; 17(5):4133-4138, 2019

DOI: 10.3892/ol.2018.9736.


  1. Tanase C, Albulescu R, Neagu M, Updates in immune-based multiplex assays, Journal of Immunoassay and Immunochemisry; 40(1):1-2, 2019

DOI: 10.1080/15321819.2019.1565064.


  1. Popa ML, Albulescu R, Neagu M, Hinescu ME, Tanase C, Multiplex assay for multiomics advances in personalized-precision medicine, Journal of Immunoassay and Immunochemistry;40(1):3-25, 2019

DOI: 10.1080/15321819.2018.1562940.

  1. Mihai S, Codrici E, Popescu ID, Enciu AM, Albulescu L, Necula LG, Mambet C, Anton G, Tanase C, Inflammation-Related Mechanisms in Chronic Kidney Disease Prediction, Progression, and Outcome, Journal of Immunology Research; ID: 2180373, 2018

DOI: 10.1155/2018/2180373.

  1. Codrici E, Albulescu L, Popescu ID, Mihai S, Enciu AM, Albulescu R, Tanase C, Hinescu ME, Caveolin-1-Knockout Mouse as a Model of Inflammatory Diseases, Journal of Immunology Research; ID: 2498576, 2018

DOI: 10.1155/2018/2498576.

  1. Ionescu IC, Corbu CG, Tanase C, Ionita G, Nicula C, Coviltir V, Potop V, Constantin M, Codrici E, Mihai S, Popescu ID, Enciu AM, Dascalescu D, Burcel M, Ciuluvica R, Voinea LM. Overexpression of Tear Inflammatory Cytokines as Additional Finding in Keratoconus Patients and Their First Degree Family Members. Mediators of Inflammation; ID: 4285268, 2018

DOI: 10.1155/2018/4285268.


  1. Pop S, Enciu AM, Necula LG, Tanase C, Long non-coding RNAs in brain tumours: Focus on recent epigenetic findings in glioma. Journal of Cellular and Molecular Medicine, 22(10):4597-4610, 2018

doi: 10.1111/jcmm.13781.


  1. Mambet C, Necula L, Mihai S, Matei L, Bleotu C, Chivu-Economescu M, Stanca O, Tatic A, Berbec N, Tanase C, Diaconu CC, Increased Dkk-1 plasma levels may discriminate disease subtypes in myeloproliferative neoplasms, Journal of Cellular and Molecular Medicine; 22(8):4005-11, 2018.

DOI: 10.1111/jcmm.13753.


  1. Solomon I, Voiculescu VM, Caruntu C, Lupu M, Popa A, Ilie MA, Albulescu R, Caruntu A, Tanase C, Constantin C, Neagu M, Boda D, Neuroendocrine Factors and Head and Neck Squamous Cell Carcinoma: An Affair to Remember, Disease Markers.; ID:9787831, 2018

DOI: 10.1155/2018/9787831.


  1. Enciu AM, Radu E, Popescu ID, Hinescu ME, Ceafalan LC, Targeting CD36 as Biomarker for Metastasis Prognostic: How Far from Translation into Clinical Practice? Biomed Res Int.; ID:7801202, 2018

doi: 10.1155/2018/7801202.


  1. Ceafalan LC, Enciu AM, Fertig TE, Popescu BO, Gherghiceanu M, Hinescu ME, Radu E, Heterocellular molecular contacts in the mammalian stem cell niche. Eur J Cell Biol., 97(6):442-461, 2018

 doi: 10.1016/j.ejcb.2018.07.001.


  1. Chivu-Economescu M, Dragu DL, Necula LG, Matei L, Enciu AM, Bleotu C, Diaconu CC. Knockdown of KRT17 by siRNA induces antitumoral effects on gastric cancer cells. Gastric Cancer, 20(6):948-959, 2017

DOI: 10.1007/s10120-017-0712-y.


  1. Solomon I, Voiculescu VM, Caruntu C, Lupu M, Popa A, Ilie MA, Albulescu R, Caruntu A, Tanase C, Constantin C, Neagu M, Boda D, Neuroendocrine Factors and Head and Neck Squamous Cell Carcinoma: An Affair to Remember, Disease Markers; ID:9787831, 2018

doi: 10.1155/2018/9787831.

  1. Chivu-Economescu M, Dragu DL, Necula LG, Matei L, Enciu AM, Bleotu C, Diaconu CC. Knockdown of KRT17 by siRNA induces antitumoral effects on gastric cancer cells. Gastric Cancer, 20(6):948-959, 2017

DOI: 10.1007/s10120-017-0712-y.


  1. Solomon I, Voiculescu VM, Caruntu C, Lupu M, Popa A, Ilie MA, Albulescu R, Caruntu A, Tanase C, Constantin C, Neagu M, Boda D, Neuroendocrine Factors and Head and Neck Squamous Cell Carcinoma: An Affair to Remember, Disease Markers; ID:9787831, 2018

doi: 10.1155/2018/9787831.

  1. Tanase CP, Codrici E, Popescu ID, Mihai S, Enciu AM, Necula LG, Preda A, Ismail G, Albulescu R. Prostate cancer proteomics: Current trends and future perspectives for biomarker discovery. Oncotarget, 8(11):18497-18512, 2017

DOI: 10.18632/oncotarget.14501.

  1. Mihai S, Codrici E, Popescu ID, Enciu AM, Rusu E, Zilisteanu D, Albulescu R, Anton G, Tanase C, Proteomic Biomarkers Panel: New Insights in Chronic Kidney Disease, Disease Markers, ID: 3185232, 2016

      DOI: 10.1155/2016/3185232.

  1. E Codrici, AM Enciu, ID Popescu, S Mihai, C Tanase, Glioma Stem Cells and their Microenvironments – Providers of Challenging Therapeutic Targets, Stem Cells International, ID:5728438, 2016

DOI: 10.1155/2016/5728438

  1. Ionescu C, Corbu CG, Tanase C, Jonescu-Cuypers C, Nicula C, Dascalescu D, Cristea M, Voinea LM. Inflammatory Biomarkers Profile as Microenvironmental Expression in Keratoconus, Disease Markers; ID:1243819, 2016

DOI: 10.1155/2016/1243819.

    1. Enciu AM, Popescu LM, Telopodes of telocytes are influenced in vitro by redox conditions and ageing.

    Mol Cell Biochem.;410(1-2):165-74, 2015

    doi: 10.1007/s11010-015-2548-2.


    1. Caravia L, Dudau M, Gherghiceanu M, Tanase C, Enciu AM. Could caveolae be acting as warnings of mitochondrial ageing? Mech Ageing Dev.;146-148:81-7, 2015

    DOI: 10.1016/j.mad.2015.04.003.

    1. Petrache Voicu SN, Dinu D, Sima C, Hermenean A, Ardelean A, Codrici E, Stan MS, Zărnescu O, Dinischiotu A. Silica Nanoparticles Induce Oxidative Stress and Autophagy but Not Apoptosis in the MRC-5 Cell Line. International Journal of Molecular Sciences.16(12):29398-416, 2015

    DOI: 10.3390/ijms161226171.

    1. R Albulescu, C Tanase, E Codrici, DI Popescu, SM Cretoiu, LM.Popescu, The secretome of myocardial telocytes modulates the activity of cardiac stem cells, Journal of Cellular and Molecular Medicine, 19(8): 1783-94, 2015

    DOI: 10.1111/jcmm.12624.

    1. Tanase C, Albulescu R, Codrici E, Popescu ID, Mihai S, Enciu AM, Cruceru ML, Popa AC, Neagu AI, Necula LG, Mambet C, Neagu M, Circulating biomarker panels for targeted therapy in brain tumors. Future Oncology., 11(3):511-24, 2015

    DOI: 10.2217/fon.14.238


    1. Neagu M, Albulescu R, Tanase C, Biotechnology landscape in cancer drug discovery, Future Sci OA; 1(3):FSO12, 2015

    DOI: 10.4155/fso.15.10.

  1. Tanase C, Albulescu R, Codrici E, Calenic B, Popescu ID, Mihai S, Necula L, Cruceru ML, Hinescu ME. Decreased expression of APAF-1 and increased expression of cathepsin B in invasive pituitary adenoma. OncoTargets and Therapy.8:81-90, 2014

DOI: 10.2147/OTT.S70886

  1. ID Popescu, E Codrici, L Albulescu, S Mihai, AM Enciu, R Albulescu, C Pistol Tanase, Potential serum biomarkers for glioblastoma diagnostic assessed by proteomic approaches, Proteome Science, 12(1):47, 2014

DOI: 10.1186/s12953-014-0047-0.


  1. Tanase CP, Neagu AI, Necula LG, Mambet C, Enciu AM, Calenic B, Cruceru ML, Albulescu R. Cancer stem cells: involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics. World J Gastroenterol., 20(31):10790-801, 2014

DOI: 10.3748/wjg.v20.i31.10790.


  1. Gheorghisan-Galateanu AA, Hinescu ME, Enciu AM, Ovarian adult stem cells: hope or pitfall? J Ovarian Res., 7:71, 2014

doi: 10.1186/1757-2215-7-71.

  1. Gheorghiu M, Enciu AM, Popescu BO, Gheorghiu E, Functional and molecular characterization of the effect of amyloid-β42 on an in vitro epithelial barrier model, J Alzheimers Dis.; 38(4):787-98, 2014.

DOI: 10.3233/JAD-122374.

  1. AC Popa, GE Stan, MA Husanu, I Pasuk, ID Popescu, AC Popescu, IN Mihailescu, Multi-layer haemocompatible diamond-like carbon coatings obtained by combined radio frequency plasma-enhanced chemical vapor deposition and magnetron sputtering, J Mater Sci Mater Med; 24(12): 2695-2707, 2013

DOI: 10.1007/s10856-013-5026-y

  1. C Tănase, E Codrici, ID Popescu, ML Cruceru, AM Enciu, R Albulescu, V Ciubotaru, D Arsene, Angiogenic markers: molecular targets for personalized medicine in pituitary adenoma, Personalized Medicine, 10(6): 539-548, 2013

DOI: 10.2217/pme.13.61

  1. R Albulescu, E Codrici, ID Popescu, S Mihai, LG Necula, D Petrescu, M Teodoru, C Pistol Tănase, Cytokine Patterns in Brain Tumour Progression, Mediators of Inflammation, ID:979748, 2013 DOI:10.1155/2013/979748


  1. Cruceru ML, Enciu AM, Popa AC, Albulescu R, Neagu M, Tanase CP, Constantinescu SN, Signal transduction molecule patterns indicating potential glioblastoma therapy approaches, OncoTargets and Therapy; 6:1737-49, 2013

DOI: 10.2147/OTT.S52365


  1. Tanase CP, Enciu AM, Mihai S, Neagu AI, Calenic B, Cruceru ML, Anti-cancer Therapies in High Grade Gliomas, Current Proteomics, 10(3):246-260, 2013

DOI: 10.2174/1570164611310030007


  1. E Duda, E Codrici, DI Popescu, L Necula, R Albulescu, Protein biomarkers in cancers of the digestive tract – a step towards personalized medicine, Current Proteomics, 10(3): 228 – 236, 2013

DOI: 10.2174/1570164611310030005


  1. Enciu AM, Popescu BO. Is there a causal link between inflammation and dementia? Biomed Res Int.; ID:316495, 2013

DOI: 10.1155/2013/316495


  1. Enciu AM, Gherghiceanu M, Popescu BO, Triggers and effectors of oxidative stress at blood-brain barrier level: relevance for brain ageing and neurodegeneration. Oxid Med Cell Longev.; ID:297512, 2013

DOI: 10.1155/2013/297512.

  1. Dima SO, Tanase C, Albulescu R, Herlea V, Chivu-Economescu M, Purnichescu-Purtan R, Dumitrascu T, Duda DG, Popescu I, An exploratory study of inflammatory cytokines as prognostic biomarkers in patients with ductal pancreatic adenocarcinoma, Pancreas; 41(7):1001-7, 2012

DOI: 10.1097/MPA.0b013e3182546e13.


  1. Neagu M, Albulescu R, Tanase C, New marker related to cancer neoangiogenesis: RGS5, Biomark Med.;6(2):197-8, 2012

DOI: 10.2217/BMM.12.5.


  1. Neagu M, Albulescu R, Tanase C, Distinct soluble EGFR isoforms expressed in non-small-cell lung cancer cells compared with normal tissue, Biomark Med.; 6(2):198-9, 2012

DOI: 10.2217/BMM.12.5.


  1. Neagu M, Albulescu R, Tanase C, An interplay between epithelial: mesenchymal transition and reverse: gene patterns for tumorigenesis, Biomark Med.;6(2):199-200, 2012

DOI: 10.2217/BMM.12.5.


  1. Enciu AM, Popescu BO, Gheorghisan-Galateanu A, MicroRNAs in brain development and degeneration, Mol Biol Rep.; 39(3):2243-52, 2012

DOI: 10.1007/s11033-011-0973-1.

  1. Tanase CP, Albulescu R, Neagu M, Application of 3D hydrogel microarrays in molecular diagnostics: advantages and limitations, Expert Rev Mol Diagn;11(5):461-4, 2011

DOI: 10.1586/erm.11.30.


  1. Enciu AM, Constantinescu SN, Popescu LM, Mureşanu DF, Popescu BO, Neurobiology of vascular dementia. J Aging Res.; ID:401604, 2011

DOI: 10.4061/2011/401604.


  1. Enciu AM, Nicolescu MI, Manole CG, Mureşanu DF, Popescu LM, Popescu BO, Neuroregeneration in neurodegenerative disorders, BMC Neurol.; 11:75, 2011

DOI: 10.1186/1471-2377-11-75.